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Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues.

Monoclonal antibody MRK16 was used to determine the location of P-glycoprotein, the product of the multidrug-resistance gene (MDR1), in normal human tissues. The protein was found to be concentrated in a small number of specific sites. Most tissues examined revealed very little P-glycoprotein. Howev...

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Autori principali: Thiebaut, F, Tsuruo, T, Hamada, H, Gottesman, M M, Pastan, I, Willingham, M C
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1987
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC299375/
https://ncbi.nlm.nih.gov/pubmed/2444983
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