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Enhancement of toxicity of antitransferrin receptor antibody-Pseudomonas exotoxin conjugates by adenovirus.

Cytotoxic conjugates were constructed by chemically coupling Pseudomonas exotoxin to antitransferrin receptor antibodies. Toxicity of these conjugates, due to entry via the transferrin receptor, was enhanced 100- to 300-fold in the presence of adenovirus. By electron microscopy and immunofluorescenc...

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Bibliografske podrobnosti
Main Authors: FitzGerald, D J, Trowbridge, I S, Pastan, I, Willingham, M C
Format: Artigo
Jezik:Inglês
Izdano: 1983
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC394215/
https://ncbi.nlm.nih.gov/pubmed/6306663
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