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Role of a low-pH environment in adenovirus enhancement of the toxicity of a Pseudomonas exotoxin-epidermal growth factor conjugate.

A conjugate of Pseudomonas exotoxin and epidermal growth factor (PE-EGF) inhibits proteins synthesis in KB cells, and this inhibition is increased by adenovirus. Protein synthesis inhibition is dependent on the amount of adenovirus and PE-EGF used and the time of incubation of cells with these agent...

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Pubblicato in:J Virol
Autori principali: Seth, P, Fitzgerald, D J, Willingham, M C, Pastan, I
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1984
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC255819/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6332200/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.51.3.650-655.1984
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