Enhancement of toxicity of antitransferrin receptor antibody-Pseudomonas exotoxin conjugates by adenovirus.

Cytotoxic conjugates were constructed by chemically coupling Pseudomonas exotoxin to antitransferrin receptor antibodies. Toxicity of these conjugates, due to entry via the transferrin receptor, was enhanced 100- to 300-fold in the presence of adenovirus. By electron microscopy and immunofluorescenc...

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Опубліковано в::	Proc Natl Acad Sci U S A
Автори:	FitzGerald, D J, Trowbridge, I S, Pastan, I, Willingham, M C
Формат:	Artigo
Мова:	Inglês
Опубліковано:	National Academy of Sciences 1983
Предмети:	Research Article
Онлайн доступ:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394215/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6306663/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.13.4134
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