Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues.

Monoclonal antibody MRK16 was used to determine the location of P-glycoprotein, the product of the multidrug-resistance gene (MDR1), in normal human tissues. The protein was found to be concentrated in a small number of specific sites. Most tissues examined revealed very little P-glycoprotein. Howev...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Thiebaut, F, Tsuruo, T, Hamada, H, Gottesman, M M, Pastan, I, Willingham, M C
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1987
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299375/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2444983/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.21.7735
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