Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues.

Monoclonal antibody MRK16 was used to determine the location of P-glycoprotein, the product of the multidrug-resistance gene (MDR1), in normal human tissues. The protein was found to be concentrated in a small number of specific sites. Most tissues examined revealed very little P-glycoprotein. Howev...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Thiebaut, F, Tsuruo, T, Hamada, H, Gottesman, M M, Pastan, I, Willingham, M C
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1987
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299375/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2444983/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.21.7735
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