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Polyphosphate exerts differential effects on blood clotting, depending on polymer size
Polyphosphate, a linear polymer of inorganic phosphate, is secreted by activated platelets and accumulates in many infectious microorganisms. We recently showed that polyphosphate modulates the blood coagulation cascade at 3 steps: it triggers the contact pathway, it accelerates factor V activation,...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society of Hematology
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2993633/ https://ncbi.nlm.nih.gov/pubmed/20709905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-266791 |
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