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Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase

Defining the links between cell division and DNA replication is essential for understanding normal cell cycle progression and tumorigenesis. In this report we explore the effect of phosphorylation of cell division cycle 6 (Cdc6), a DNA replication initiation factor, by polo-like kinase 1 (Plk1) on t...

詳細記述

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書誌詳細
主要な著者: Yim, Hyungshin, Erikson, Raymond L.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993418/
https://ncbi.nlm.nih.gov/pubmed/21041660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013557107
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