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Regulation of the final stage of mitosis by components of the pre-replicative complex and a polo kinase

The accurate division of duplicated DNA is essential for maintenance of genomic stability in proliferating eukaryotic cells. Errors in DNA replication and chromosomal segregation may lead to cell death or genomic mutations that lead to oncogenic properties. Thus, tight regulation of DNA replication...

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Autori principali: Yim, Hyungshin, Erikson, Raymond L
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117042/
https://ncbi.nlm.nih.gov/pubmed/21519187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.9.15489
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