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Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase

Defining the links between cell division and DNA replication is essential for understanding normal cell cycle progression and tumorigenesis. In this report we explore the effect of phosphorylation of cell division cycle 6 (Cdc6), a DNA replication initiation factor, by polo-like kinase 1 (Plk1) on t...

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Hlavní autoři: Yim, Hyungshin, Erikson, Raymond L.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993418/
https://ncbi.nlm.nih.gov/pubmed/21041660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013557107
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