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Toll-like Receptor-7 Mediates Pruritus
Toll-like receptors (TLRs) are typically expressed in immune cells to regulate innate immunity. Here we report that functional TLR7 is expressed in C-fiber primary sensory neurons and important for inducing itch (pruritis) but not necessary for eliciting mechanical, thermal, inflammatory and neuropa...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2991508/ https://ncbi.nlm.nih.gov/pubmed/21037581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2683 |
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