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TNF-α contributes to spinal cord synaptic plasticity and inflammatory pain: Distinct role of TNF receptor subtype 1 and 2

Tumor necrosis factor-alpha (TNF-α) is a key proinflammatory cytokine. It is generally believed that TNF-α exerts its effects primarily via TNF receptor subtype-1 (TNFR1). We investigated distinct role of TNFR1 and TNFR2 in spinal cord synaptic transmission and inflammatory pain. Compared to wild-ty...

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Библиографические подробности
Главные авторы: Zhang, Ling, Berta, Temugin, Xu, Zhen-Zhong, Liu, Tong, Park, Jong Yeon, Ji, Ru-Rong
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022092/
https://ncbi.nlm.nih.gov/pubmed/21159431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2010.11.014
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