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Extracellular microRNAs activate nociceptor neurons to elicit pain via TLR7 and TRPA1
Intracellular microRNAs (miRNAs) are key regulators of gene expression. The role of extracellular miRNAs in neuronal activation and sensory behaviors are unknown. Here we report an unconventional role of extracellular miRNAs for rapid excitation of nociceptor neurons via toll-like receptor-7 (TLR7)...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3982230/ https://ncbi.nlm.nih.gov/pubmed/24698267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.02.011 |
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