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Toll-like Receptor-7 Mediates Pruritus

Toll-like receptors (TLRs) are typically expressed in immune cells to regulate innate immunity. Here we report that functional TLR7 is expressed in C-fiber primary sensory neurons and important for inducing itch (pruritis) but not necessary for eliciting mechanical, thermal, inflammatory and neuropa...

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Detalhes bibliográficos
Main Authors: Liu, Tong, Xu, Zhen-Zhong, Park, Chul-Kyu, Berta, Temugin, Ji, Ru-Rong
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991508/
https://ncbi.nlm.nih.gov/pubmed/21037581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2683
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