CpG Demethylation Enhances Alpha-Synuclein Expression and Affects the Pathogenesis of Parkinson's Disease

BACKGROUND: Alpha-synuclein (SNCA) gene expression is an important factor in the pathogenesis of Parkinson's disease (PD). Gene multiplication can cause inherited PD, and promoter polymorphisms that increase SNCA expression are associated with sporadic PD. CpG methylation in the promoter region...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Matsumoto, Lumine, Takuma, Hiroshi, Tamaoka, Akira, Kurisaki, Hiroshi, Date, Hidetoshi, Tsuji, Shoji, Iwata, Atsushi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991358/
https://ncbi.nlm.nih.gov/pubmed/21124796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015522
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados