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Early demethylation of non-CpG, CpC-rich, elements in the myogenin 5′-flanking region: A priming effect on the spreading of active demethylation?

The dynamic changes and structural patterns of DNA methylation of genes without CpG islands are poorly characterized. The relevance of CpG to the non-CpG methylation equilibrium in transcriptional repression is unknown. In this work, we analyzed the DNA methylation pattern of the 5′-flanking of the...

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Detalhes bibliográficos
Main Authors: Fuso, Andrea, Ferraguti, Giampiero, Grandoni, Francesco, Ruggeri, Raffaella, Scarpa, Sigfrido, Strom, Roberto, Lucarelli, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047754/
https://ncbi.nlm.nih.gov/pubmed/20935518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.19.13193
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