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A specific CpG site demethylation in the human interleukin 2 gene promoter is an epigenetic memory
DNA demethylation plays a critical role in transcriptional regulation in differentiated somatic cells. However, there is no experimental evidence that CpG methylation in a small region of a genome restricts gene expression. Here, we show that the anti-CD3ɛ/CD28 antibody stimulation of human CD4(+) T...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1409718/ https://ncbi.nlm.nih.gov/pubmed/16498406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601012 |
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