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GPVI Potentiation of Platelet Activation by Thrombin and Adhesion Molecules Independent of Src Kinases and Syk
OBJECTIVE: The present study investigates the role of Src and Syk tyrosine kinases in signaling by G-protein coupled and platelet adhesion receptors. METHODS AND RESULTS: Using Syk(−/−) platelets or the Src kinase inhibitor PP2, we demonstrate a critical role for Src and Syk kinases in mediating lam...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2990469/ https://ncbi.nlm.nih.gov/pubmed/17110603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.ATV.0000252826.96134.21 |
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