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A major role for Scar/WAVE-1 downstream of GPVI in platelets
BACKGROUND: The small GTPase Rac1 plays a critical role in lamellipodia assembly in platelets on matrix proteins in the absence or presence of G protein-coupled receptor (GPCR) agonists. Rac mediates actin assembly via Scar/WAVE, a family of scaffolding proteins that direct actin reorganization by r...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1880834/ https://ncbi.nlm.nih.gov/pubmed/17319906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2007.02377.x |
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