Laminin stimulates spreading of platelets through integrin α(6)β(1)–dependent activation of GPVI

The extracellular matrix protein, laminin, supports platelet adhesion through binding to integrin α(6)β(1) In the present study, we demonstrate that human laminin, purified from placenta, also stimulates formation of filopodia and lamellipodia in human and mouse platelets through a pathway that is d...

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Detalhes bibliográficos
Main Authors: Inoue, Osamu, Suzuki-Inoue, Katsue, McCarty, Owen J. T., Moroi, Masaaki, Ruggeri, Zaverio M., Kunicki, Thomas J., Ozaki, Yukio, Watson, Steve P.
Formato: Artigo
Idioma:Inglês
Publicado em: © 2006 by The American Society of Hematology 2006
Assuntos:
Hemostasis, Thrombosis, and Vascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895394/
https://ncbi.nlm.nih.gov/pubmed/16219796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-06-2406
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