Laminin stimulates spreading of platelets through integrin α(6)β(1)–dependent activation of GPVI

The extracellular matrix protein, laminin, supports platelet adhesion through binding to integrin α(6)β(1) In the present study, we demonstrate that human laminin, purified from placenta, also stimulates formation of filopodia and lamellipodia in human and mouse platelets through a pathway that is d...

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Bibliographische Detailangaben
Hauptverfasser: Inoue, Osamu, Suzuki-Inoue, Katsue, McCarty, Owen J. T., Moroi, Masaaki, Ruggeri, Zaverio M., Kunicki, Thomas J., Ozaki, Yukio, Watson, Steve P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: © 2006 by The American Society of Hematology 2006
Schlagworte:
Hemostasis, Thrombosis, and Vascular Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895394/
https://ncbi.nlm.nih.gov/pubmed/16219796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-06-2406
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