The structural basis for catalysis and substrate specificity of a rhomboid protease

Rhomboids are intramembrane proteases that use a catalytic dyad of serine and histidine for proteolysis. They are conserved in both prokaryotes and eukaryotes and regulate cellular processes as diverse as intercellular signalling, parasitic invasion of host cells, and mitochondrial morphology. Their...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Vinothkumar, Kutti R, Strisovsky, Kvido, Andreeva, Antonina, Christova, Yonka, Verhelst, Steven, Freeman, Matthew
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2010
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989101/
https://ncbi.nlm.nih.gov/pubmed/20890268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.243
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