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The structural basis for catalysis and substrate specificity of a rhomboid protease
Rhomboids are intramembrane proteases that use a catalytic dyad of serine and histidine for proteolysis. They are conserved in both prokaryotes and eukaryotes and regulate cellular processes as diverse as intercellular signalling, parasitic invasion of host cells, and mitochondrial morphology. Their...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2989101/ https://ncbi.nlm.nih.gov/pubmed/20890268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.243 |
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