The structural basis for catalysis and substrate specificity of a rhomboid protease

Rhomboids are intramembrane proteases that use a catalytic dyad of serine and histidine for proteolysis. They are conserved in both prokaryotes and eukaryotes and regulate cellular processes as diverse as intercellular signalling, parasitic invasion of host cells, and mitochondrial morphology. Their...

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Detaylı Bibliyografya
Asıl Yazarlar: Vinothkumar, Kutti R, Strisovsky, Kvido, Andreeva, Antonina, Christova, Yonka, Verhelst, Steven, Freeman, Matthew
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989101/
https://ncbi.nlm.nih.gov/pubmed/20890268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.243
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