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Sharpening rhomboid specificity by dimerisation and allostery
In this issue of The EMBO Journal, mechanistic analyses of substrate cleavage by rhomboid intramembrane proteases suggest that catalytic efficiency towards natural, transmembrane substrates is allosterically stimulated by initial substrate interaction with an intramembrane exosite, whose formation d...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4195779/ https://ncbi.nlm.nih.gov/pubmed/25027763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201489373 |
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