Rhomboid Family Pseudoproteases Use the ER Quality Control Machinery to Regulate Intercellular Signaling

Intramembrane proteolysis governs many cellular control processes, but little is known about how intramembrane proteases are regulated. iRhoms are a conserved subfamily of proteins related to rhomboid intramembrane serine proteases that lack key catalytic residues. We have used a combination of gene...

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Bibliographic Details
Main Authors:	Zettl, Markus, Adrain, Colin, Strisovsky, Kvido, Lastun, Viorica, Freeman, Matthew
Format:	Artigo
Language:	Inglês
Published:	Cell Press 2011
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3149277/ https://ncbi.nlm.nih.gov/pubmed/21439629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.02.047
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Rhomboid Family Pseudoproteases Use the ER Quality Control Machinery to Regulate Intercellular Signaling

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