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Rhomboid Family Pseudoproteases Use the ER Quality Control Machinery to Regulate Intercellular Signaling

Intramembrane proteolysis governs many cellular control processes, but little is known about how intramembrane proteases are regulated. iRhoms are a conserved subfamily of proteins related to rhomboid intramembrane serine proteases that lack key catalytic residues. We have used a combination of gene...

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Hlavní autoři: Zettl, Markus, Adrain, Colin, Strisovsky, Kvido, Lastun, Viorica, Freeman, Matthew
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149277/
https://ncbi.nlm.nih.gov/pubmed/21439629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.02.047
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