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Rhomboid Family Pseudoproteases Use the ER Quality Control Machinery to Regulate Intercellular Signaling

Intramembrane proteolysis governs many cellular control processes, but little is known about how intramembrane proteases are regulated. iRhoms are a conserved subfamily of proteins related to rhomboid intramembrane serine proteases that lack key catalytic residues. We have used a combination of gene...

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Detalles Bibliográficos
Main Authors: Zettl, Markus, Adrain, Colin, Strisovsky, Kvido, Lastun, Viorica, Freeman, Matthew
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149277/
https://ncbi.nlm.nih.gov/pubmed/21439629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.02.047
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