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Monocyclic β-Lactams Are Selective, Mechanism-Based Inhibitors of Rhomboid Intramembrane Proteases
[Image: see text] Rhomboids are relatively recently discovered intramembrane serine proteases that are conserved throughout evolution. They have a wide range of biological functions, and there is also much speculation about their potential medical relevance. Although rhomboids are weakly inhibited b...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Chemical Society
2010
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3077804/ https://ncbi.nlm.nih.gov/pubmed/21175222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb100314y |
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