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Monocyclic β-Lactams Are Selective, Mechanism-Based Inhibitors of Rhomboid Intramembrane Proteases
[Image: see text] Rhomboids are relatively recently discovered intramembrane serine proteases that are conserved throughout evolution. They have a wide range of biological functions, and there is also much speculation about their potential medical relevance. Although rhomboids are weakly inhibited b...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Chemical Society
2010
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| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3077804/ https://ncbi.nlm.nih.gov/pubmed/21175222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb100314y |
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