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An Assessment of Chemoselective Neoglycosylation Methods Using Chlorambucil as a Model
To systematically assess the impact of glycosylation and the corresponding chemoselective linker upon the anticancer activity/selectivity of the drug chlorambucil, herein we report the synthesis and anticancer activities of a 63-member library of chlorambucil-based neoglycosides. A comparison of N-a...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2988911/ https://ncbi.nlm.nih.gov/pubmed/20973561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm101024j |
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