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Enhancement of Cyclopamine via Conjugation with Non-metabolic Sugars
[Image: see text] The Veratrum alkaloid cyclopamine, an inhibitor of cancer stem cell growth, was used as a representative scaffold to evaluate the inhibitory impact of glycosylation with a group of non-metabolic saccharides, such as D-threose. In a five-step divergent process, a 32-member glycoside...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3442133/ https://ncbi.nlm.nih.gov/pubmed/22540932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol300703z |
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