Heteronanoparticles by self-Assembly of Doxorubicin and Cyclopamine Conjugates

[Image: see text] The preparation of heteronanoparticles (NPs) with doxorubicin (DOXO) and cyclopamine (CYP) conjugates is presented. Biological evaluation on A431 cell lines confirms the maintenance of the activity of the parental drugs. The in vivo study shows that self-assembled NPs reduce tumor...

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Bibliographic Details
Published in:ACS Med Chem Lett
Main Authors: Fumagalli, Gaia, Stella, Barbara, Pastushenko, Ievgenia, Ricci, Francesca, Christodoulou, Michael S., Damia, Giovanna, Mazza, Davide, Arpicco, Silvia, Giannini, Clelia, Morosi, Lavinia, Dosio, Franco, Sotiropoulou, Panagiota A., Passarella, Daniele
Format: Artigo
Language:Inglês
Published: American Chemical Society 2017
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601370/
https://ncbi.nlm.nih.gov/pubmed/28947943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.7b00262
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