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Neoglycosylation and neoglycorandomization: Enabling tools for the discovery of novel glycosylated bioactive probes and early stage leads

This review focuses upon the development, scope, and utility of the highly versatile chemoselective alkoxyamine-based ‘neoglycosylation’ reaction first described by Peri and Dumy. The fundamentals of neoglycosylation and the subsequent development of a ‘neoglycorandomization’ platform to afford diff...

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Autors principals: Goff, Randal D., Thorson, Jon. S.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111257/
https://ncbi.nlm.nih.gov/pubmed/25071927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C4MD00117F
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