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Natural product disaccharide engineering through tandem glycosyltransferase catalysis reversibility and neoglycosylation
[Image: see text] A two-step strategy for disaccharide modulation using vancomycin as a model is reported. The strategy relies upon a glycosyltransferase-catalyzed ‘reverse’ reaction to enable the facile attachment of an alkoxyamine-bearing sugar to the vancomycin core. Neoglycosylation of the corre...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3489467/ https://ncbi.nlm.nih.gov/pubmed/22984807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol3023374 |
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