DNA Minor Groove Induced Dimerization of Heterocyclic Cations: Compound Structure, Binding Affinity and Specificity for a TTAA Site

With the increasing number and variations of genome sequences available control of gene expression with synthetic, cell permeable molecules is within reach. The variety of sequence-specific-binding agents is, however, still quite limited. Many minor groove binding agents selectivity recognize AT ove...

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Main Authors: Munde, Manoj, Kumar, Arvind, Nhili, Raja, Depauw, Sabine, David-Cordonnier, Marie-Hélène, Ismail, Mohamed A., Stephens, Chad E., Farahat, Abdelbasset A., Batista-Parra, Adalgisa, Boykin, David W., Wilson, W. David
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988403/
https://ncbi.nlm.nih.gov/pubmed/20713062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.08.018
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