Macroautophagy Is Not Directly Involved in the Metabolism of Amyloid Precursor Protein

Alterations in the metabolism of amyloid precursor protein (APP) are believed to play a central role in Alzheimer disease pathogenesis. Burgeoning data indicate that APP is proteolytically processed in endosomal-autophagic-lysosomal compartments. In this study, we used both in vivo and in vitro para...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Boland, Barry, Smith, David A., Mooney, Declan, Jung, Sonia S., Walsh, Dominic M., Platt, Frances M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988347/
https://ncbi.nlm.nih.gov/pubmed/20864542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.186411
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados