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Macroautophagy Is Not Directly Involved in the Metabolism of Amyloid Precursor Protein
Alterations in the metabolism of amyloid precursor protein (APP) are believed to play a central role in Alzheimer disease pathogenesis. Burgeoning data indicate that APP is proteolytically processed in endosomal-autophagic-lysosomal compartments. In this study, we used both in vivo and in vitro para...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular
Biology
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2988347/ https://ncbi.nlm.nih.gov/pubmed/20864542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.186411 |
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