ATM-independent, high-fidelity nonhomologous end joining predominates in human embryonic stem cells

We recently demonstrated that human embryonic stem cells (hESCs) utilize homologous recombination repair (HRR) as primary means of double-strand break (DSB) repair. We now show that hESCs also use nonhomologous end joining (NHEJ). NHEJ kinetics were several-fold slower in hESCs and neural progenitor...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Adams, Bret R., Hawkins, Amy J., Povirk, Lawrence F., Valerie, Kristoffer
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2010
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984607/
https://ncbi.nlm.nih.gov/pubmed/20844317
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars