The fidelity of the ligation step determines how ends are resolved during Nonhomologous end joining

Nonhomologous end joining (NHEJ) can effectively resolve chromosome breaks despite diverse end structures, but it is unclear how the steps employed for resolution are determined. We sought to address this question by analyzing cellular NHEJ of ends with systematically mispaired and damaged termini....

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Hauptverfasser: Waters, Crystal A., Strande, Natasha T., Pryor, John M., Strom, Christina, Mieczkowski, Piotr, Burkhalter, Martin D., Oh, Sehyun, Qaqish, Bahjat F., Moore, Dominic T., Hendrickson, Eric A., Ramsden, Dale A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4107315/
https://ncbi.nlm.nih.gov/pubmed/24989324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5286
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