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Phosphorylation of Ser312 contributes to tumor suppression by p53 in vivo
The tumor suppressor p53 is a master sensor of stress, and posttranslational modifications are key in controlling its stability and transcriptional activities. p53 can be phosphorylated on at least 23 Ser/Thr residues, the majority of which are phosphorylated by stress-related kinases. An exception...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2984175/ https://ncbi.nlm.nih.gov/pubmed/20962274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005165107 |
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