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Molecular analysis of O6-substituted guanine-induced mutagenesis of ras oncogenes.
We have designed an Ha-ras/thymidine kinase (TK) cassette that permits the incorporation of chemically synthesized adducts within specific domains of the rat Ha-ras protooncogene. This cassette has been used to evaluate the mutagenicity of O6-substituted guanine residues, including O6-methylguanine...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
1989
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298345/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2682655/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.22.8650 |
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