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Antitumor activity in mice of an immunotoxin made with anti-transferrin receptor and a recombinant form of Pseudomonas exotoxin.

LysPE40 is a modified form of Pseudomonas exotoxin that lacks the cell-binding domain and has a chemically reactive lysine residue near the amino terminus. LysPE40 is made in Escherichia coli and secreted into the medium from which it is readily purified. Two immunotoxins were constructed by couplin...

詳細記述

保存先:
書誌詳細
主要な著者: Batra, J K, Jinno, Y, Chaudhary, V K, Kondo, T, Willingham, M C, FitzGerald, D J, Pastan, I
フォーマット: Artigo
言語:Inglês
出版事項: 1989
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC298319/
https://ncbi.nlm.nih.gov/pubmed/2510169
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