Antitumor activity in mice of an immunotoxin made with anti-transferrin receptor and a recombinant form of Pseudomonas exotoxin.

LysPE40 is a modified form of Pseudomonas exotoxin that lacks the cell-binding domain and has a chemically reactive lysine residue near the amino terminus. LysPE40 is made in Escherichia coli and secreted into the medium from which it is readily purified. Two immunotoxins were constructed by couplin...

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Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Batra, J K, Jinno, Y, Chaudhary, V K, Kondo, T, Willingham, M C, FitzGerald, D J, Pastan, I
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 1989
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298319/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2510169/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.21.8545
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