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Activation of the Pacidamycin PacL Adenylation Domain by MbtH-Like Proteins
Nonribosomal peptide synthetase (NRPS) assembly lines are major avenues for the biosynthesis of a vast array of peptidyl natural products. Several hundred bacterial NRPS gene clusters contain a small (~70 residue) protein belonging to the MbtH family for which no function has been defined. Here we s...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2982891/ https://ncbi.nlm.nih.gov/pubmed/20964365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101539b |
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