Role of Two Exceptional trans Adenylation Domains and MbtH‐like Proteins in the Biosynthesis of the Nonribosomal Peptide WS9324A from Streptomyces calvus ATCC 13382

Nonribosomal peptide synthetases (NRPS) are organized in a modular arrangement. Usually, the modular order corresponds to the assembly of the amino acids in the respective peptide, following the collinearity rule. The WS9326A biosynthetic gene cluster from Streptomyces calvus shows deviations from t...

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Bibliographic Details
Published in:Chembiochem
Main Authors: Bernhardt, Mirjam, Berman, Stefanie, Zechel, David, Bechthold, Andreas
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7539972/
https://ncbi.nlm.nih.gov/pubmed/32333627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.202000142
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