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Structural Basis of the Interaction of MbtH-like Proteins, Putative Regulators of Nonribosomal Peptide Biosynthesis, with Adenylating Enzymes

The biosynthesis of nonribosomally formed peptides (NRPs), which include important antibiotics such as vancomycin, requires the activation of amino acids through adenylate formation. The biosynthetic gene clusters of NRPs frequently contain genes for small, so-called MbtH-like proteins. Recently, it...

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Detalhes bibliográficos
Main Authors: Herbst, Dominik A., Boll, Björn, Zocher, Georg, Stehle, Thilo, Heide, Lutz
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548506/
https://ncbi.nlm.nih.gov/pubmed/23192349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.420182
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