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Structural Basis of the Interaction of MbtH-like Proteins, Putative Regulators of Nonribosomal Peptide Biosynthesis, with Adenylating Enzymes

The biosynthesis of nonribosomally formed peptides (NRPs), which include important antibiotics such as vancomycin, requires the activation of amino acids through adenylate formation. The biosynthetic gene clusters of NRPs frequently contain genes for small, so-called MbtH-like proteins. Recently, it...

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Autors principals: Herbst, Dominik A., Boll, Björn, Zocher, Georg, Stehle, Thilo, Heide, Lutz
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548506/
https://ncbi.nlm.nih.gov/pubmed/23192349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.420182
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