Using MbtH-like proteins to alter substrate profile of a nonribosomal peptide adenylation enzyme

MbtH-like proteins (MLPs) are required for soluble expression and/or optimal activity of some adenylation (A) domains of nonribosomal peptide synthetases (NRPSs). Since A domains can interact with noncognate MLP partners, we investigated how the function of an A domain, TioK, involved in the biosynt...

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Detalhes bibliográficos
Publicado no:Chembiochem
Main Authors: Mori, Shogo, Green, Keith D., Choi, Ryan, Buchko, Garry W., Fried, Michael G., Garneau-Tsodikova, Sylvie
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6439349/
https://ncbi.nlm.nih.gov/pubmed/30134012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201800240
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