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Integration of Clearance Mechanisms: The Proteasome and Autophagy
Cells maintain a healthy proteome through continuous evaluation of the quality of each of their proteins. Quality control requires the coordinated action of chaperones and proteolytic systems. Chaperones identify abnormal or unstable conformations in proteins and often assist them to regain stabilit...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2982176/ https://ncbi.nlm.nih.gov/pubmed/21068151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a006734 |
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