MOLECULAR DETERMINANTS OF SELECTIVE CLEARANCE OF PROTEIN INCLUSIONS BY AUTOPHAGY

Protein quality control is essential for cellular survival. Failure to eliminate pathogenic proteins leads to their intracellular accumulation in the form of protein aggregates. Autophagy can recognize protein aggregates and degrade them in lysosomes. However, some aggregates escape the autophagic s...

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Bibliografiska uppgifter
Huvudupphovsmän: Wong, Esther, Bejarano, Eloy, Rakshit, Moumita, Lee, Karen, Hanson, Hugo H., Zaarur, Nava, Phillips, Greg R., Sherman, Michael Y., Cuervo, Ana Maria
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526956/
https://ncbi.nlm.nih.gov/pubmed/23212369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2244
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