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Autophagy-mediated clearance of aggresomes is not a universal phenomenon

Aggresomes are juxtanuclear inclusion bodies that have been proposed to act as staging grounds for the disposal of protein aggregates via the autophagic route. To examine whether the composition of an aggresome influences its clearance by autophagy, we ectopically expressed a variety of aggregation-...

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Detalhes bibliográficos
Main Authors: Wong, Esther S.P., Tan, Jeanne M.M., Soong, Wen-E, Hussein, Kamila, Nukina, Nobuyuki, Dawson, Valina L., Dawson, Ted M., Cuervo, Ana Maria, Lim, Kah-Leong
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722889/
https://ncbi.nlm.nih.gov/pubmed/18502787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn157
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