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Autophagy-mediated clearance of aggresomes is not a universal phenomenon

Aggresomes are juxtanuclear inclusion bodies that have been proposed to act as staging grounds for the disposal of protein aggregates via the autophagic route. To examine whether the composition of an aggresome influences its clearance by autophagy, we ectopically expressed a variety of aggregation-...

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Autors principals: Wong, Esther S.P., Tan, Jeanne M.M., Soong, Wen-E, Hussein, Kamila, Nukina, Nobuyuki, Dawson, Valina L., Dawson, Ted M., Cuervo, Ana Maria, Lim, Kah-Leong
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722889/
https://ncbi.nlm.nih.gov/pubmed/18502787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn157
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