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Integration of Clearance Mechanisms: The Proteasome and Autophagy

Cells maintain a healthy proteome through continuous evaluation of the quality of each of their proteins. Quality control requires the coordinated action of chaperones and proteolytic systems. Chaperones identify abnormal or unstable conformations in proteins and often assist them to regain stabilit...

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Detalles Bibliográficos
Main Authors: Wong, Esther, Cuervo, Ana Maria
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982176/
https://ncbi.nlm.nih.gov/pubmed/21068151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a006734
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